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Let’s talk anti-wrinkle injectables

Let’s talk anti-wrinkle injectables

Let’s talk anti-wrinkle injectables

Discover XEOMIN®, an effective and purified* botulinum toxin.

With skin losing volume and elasticity as we age, coupled with (one would hope!) many years of laughter and expressiveness, we can begin to form movable, dynamic lines on our face that eventually settle into static lines that remain in place. Seeking out anti-wrinkle treatments to refresh your look and relax these facial lines is more popular than ever, and now readily discussed between friends.

Less commonly talked about though, are that there are a number of different options currently available, and issues such as the potential risk of developing resistance to treatment over time possibly resulting in less satisfactory results.

Did you know muscle-relaxing injections made of botulinum toxin have varying levels of protein content? What’s more, emerging therapeutic research suggests that over repeated treatments, the total dose level and protein amount injected may influence how effective each result is, and how long it will last over time. Increasing therapeutic evidence and published clinical research shows it’s possible to build up a resistance to botulinum toxins as a result of increasing doses with treatment of multiple areas over time and the presence of unnecessary proteins. That’s because in some cases, these unnecessary proteins can stimulate an immune response where you develop antibodies that prevent the treatment working as intended, meaning they become less effective over time. It may explain why you might not be seeing the long-lasting results you used to see, or you are needing higher doses of botulinum toxin to keep wrinkles at bay.

In a growing market, it’s more important than ever to seek out a reputable provider and understand how the treatment you’re having will fit with your intention and lifestyle.


XEOMIN®  is a purified* botulinum toxin, developed by Merz Aesthetics. It’s free from unnecessary proteins that may contribute to treatment resistance in some patients over time. It undergoes additional purification* steps during production to remove the complexing protein which means the end product contains only the active part of the botulinum toxin. When injected, XEOMIN® acts on the nerve endings in facial muscles and prevents them from contracting. The reduction in muscle activity temporarily softens the lines in the face, like crow’s feet, forehead creases and frown lines, with the intention of giving you a natural, well-rested appearance.


During the treatment, as administered only by an aesthetic medicine doctor or registered nurse, purified* botulinum toxin XEOMIN® is injected in minimal amounts directly to the target muscle where it reduces muscle activity. It’s a relatively quick process, with the whole procedure taking approximately 20 minutes. With no downtime, you can easily get back to the office immediately after a lunchtime treatment.

The effects of purified* botulinum toxin XEOMIN® therapy are rapid and should generally be noticeable within 2-3 days following treatment, with maximum effect visible after around one month. Retreatment will be required around four months after the initial treatment, with the effects gradually wearing off during this time. However, the duration of effect will vary between individuals, so ask your doctor when retreatment is recommended for you.


XEOMIN® is an effective, widely used anti-wrinkle option globally, with results proven in numerous clinical studies. In frown line treatment studies, XEOMIN® anti-wrinkle injections improved the appearance of frown-lines in over 95% of patients within 1 month of treatment and desirable effects were maintained for up to 4 months. Additional clinical trials have shown that XEOMIN® is also highly effective for the treatment of horizontal frown lines and crow’s feet with results maintained for up to 4 months.

* Xeomin contains zero complexing proteins.

Speak to your healthcare professional to see if XEOMIN® is right for you. For more information on XEOMIN® and how to find your local clinic, visit

Xeomin (Incobotulinumtoxin A) 50, 100 Units is a Prescription Medicine. Indications: In adults, for the treatment of cervical dystonia; blepharospasm; spasticity of the upper limb; upper facial lines: glabellar frown lines, lateral periorbital lines (crow’s feet), horizontal forehead lines. Xeomin has both risks and benefits, consult your doctor if Xeomin is right for you. Further information on the risks and benefits of Xeomin can be found in the Consumer Medicine Information (CMI) available from or by calling O800 822 310. Use strictly as directed. If symptoms continue or you have side effects, see your doctor, pharmacist or health care professional. Common side effects include: Headaches; nausea; tenderness, swelling, redness, numbness or bruising of the skin; dry eye; heavy feeling of ayelid/eyebrow/forehead; face/ brow not symmetrical, dropping eyelids/eyebrows. Serious side effects are rare and include allergic reactions. Xeomin is an unfunded medicine, prescription charge will apply. Normal doctor charges will still apply. Copyright ©2021. Pharmacy Retailing NZ Limited t/a Health Care Logistics (HCL) 58 Richard Pearse Drive, Mangere, Auckland 2022. All rights reserved. Xeomin  and Merz Aesthetics are registered trademarks of Merz Pharma GMbH & Go. KGaA. NZ_XEO_ADV_MINDF_V1:APRIL21. Date of preparation: April 2021. TAPS: MR7532

For information about how Merz handles personal data, please see Merz General Data Protection Information Notice at

* References available on request.


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