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Can fish oil enhance mental health?

Taking fish oil may help prevent full-blown psychotic illness in at-risk adolescents and young adults, according to a new study from The University of Melbourne, reports MiNDFOOD.

Can fish oil enhance mental health?

At-risk individuals may have weak or transient psychotic symptoms, and already show schizophrenia-like brain changes, Dr G. Paul Amminger of The University of Melbourne in Australia, a researcher on the study, explains. But while psychiatrists now know how to identify these individuals, he added, they don’t know what to do with them. “At the moment there’s no state-of-the-art guideline (on) how to treat those people.”

Prescribing antipsychotic medications may be helpful, Amminger added, but these medications have serious side effects, and can also be stigmatising. “For young people they don’t want to commit themselves to a treatment which they might need to take for the next five to ten years,” he said. Furthermore, only about a third of people at high risk for psychotic disorders will go on to develop full-fledged mental illness in a given year.

There’s considerable evidence that abnormal fatty acid metabolism may contribute to the development of schizophrenia, Amminger and his team note in the Archives of General Psychiatry. To investigate whether omega-3 fatty acids might help prevent psychotic illness, they randomly assigned 81 at-risk individuals, 13 to 25 years old, to take 1.2 grams a day of omega-3s in fish oil capsule form or a placebo for 12 weeks and then followed them for another 40 weeks.

The researchers included people who met at least one of the following three criteria: having low-level psychotic symptoms; having transient psychotic symptoms; or having a schizophrenia-like personality disorder or a close relative with schizophrenia, along with a sharp decline in mental function within the past year.

Seventy-six of the 81 study participants, or 94 per cent, completed the trial, Amminger noted, which underscores the safety and tolerability of fish oil.

At one year, 5 per cent of the study participants taking omega-3s had developed a psychotic disorder (2 of 41 people), compared to 28 per cent of those on placebo (11 of 40). People taking fish oil also showed significant reductions in their psychotic symptoms and improvements in function, while they were at no greater risk of adverse effects than people taking placebo capsules.

The effect of fish oil capsules, Amminger noted, was similar to that seen in two trials of antipsychotic drugs in at-risk individuals.

There are a number of mechanisms through which omega-3s could protect the brain, Amminger said; they are a major component of brain cells. They are also key to the proper function of two brain chemical signaling systems, dopamine and serotonin, which have been implicated in schizophrenia. Fish oil also boosts levels of glutathione, an antioxidant that protects the brain against oxidative stress.

Trials of medications for treating mental illness typically don’t include people younger than 18, Amminger noted, while starting minors on these medications is “always very difficult, and always quite controversial.”

But if future research bears out the current findings, he added, fish oil promises to offer a safe way to help prevent psychosis in at-risk people, and could also potentially be used to prevent or delay the onset of chronic depression, bipolar illness, and substance abuse disorder – all of which are far more common than psychotic illness.

He and his colleagues are now planning a multicentre trial of fish oil for the prevention of psychotic illness in 320 at-risk people.


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One Comment on Can fish oil enhance mental health?

  • jeanniebliss
    January 13, 2016 7:04 am

    .just printed fish oil article to take to my Dr to see she I know will agree….She knows my background and been labeled bi-polar (not by her.) Yes I do have history of anxiety and depression in 1998 or so burnt out at my job as youth worker, hospitalised and m emories of my emotional
    and physical during my childhood surfaced. My abuser was male neighbour who ‘looked after’ me if my mum and dad at work, like a movie(could feel and see it) of sexual abuse came to light, dramatically, and am still working on my tainted self beliefs and self doubt,shame and yes suicidal tendancies once never would have expressed, death was a better option I thought ???when felt this bad… Now know better to late for me to go back in time but at 70 at this moment in time want to live and be happy,hopefully hat do not go to the pits again. Writing this as much for me as you. But I started a Support group or women adult survivors of child abuse, First year (very fragile) went to councel meeting on funding for services, I was no longer able to work and was on disability, as stress situations affected me, and being watched or feeling (as this occured when i was a child, had to be a ‘good ‘ girl not complain or be sad as hat was bad,) only realise now 2016 how to see what ails me!!. This started off to tell you I do take fish oil (way the mind works always of intrest to me and if seen and heard early enough can prevent ongoinging cyclical thinking)I also wash my face each morning and rub in oil of capsul in my face do my lobs and then have shower or bath, find it benificial. This should be displayed in hospitals, doctors waiting rooms and Universitys and schools, education and awareness in most cases of mental issues there’ s an underlying cause if dealt with by many and varied means can lead healthy life.. Hope this will raise awarenes as I become more aware need to share to help others and me to heal eventually drug free, but natural remedies are made for healing

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